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La Jolla, CALIFORNIA
92038-2946
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mailing address:
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address:
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WORLD
CONGRESSES
on GENOMIC MEDICINE
NEWS on GENOMIC MEDICINE
WORLDWIDE
MEMBERSHIP
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The Stefan University
JOURNAL of
GENOMIC MEDICINE
( ISSN: 1528-4883 )
GENOMIC MEDICINE NOW
A Popular Magazine
for Genomic Medicine
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A S-G M goals
are:
To serve the GENOMIC MEDICINE
and PHARMACOGENOMICS INTERNATIONAL COMMUNITY by promoting the development and diffusion of
achievements in GENOMIC MEDICINE, and by promoting the collaborative
efforts of research centers worldwide.
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To Promote cooperation and communication
with other societies to support
the international genomic medicine community.
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To Publish a newsletter, brochures, and
other technical and scientific documents.
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To Provide an active website for
electronic access
to information of interest for genomic medicine international community.
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To Sponsor educational initiatives and
special programs
that support the development of genomic medicine.
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To Support and promote new discoveries and
applications in genomic medicine.
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To Organize workshops, short courses,
summer schools, and international congresses..
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To Facilitate technical and research
interactions between genomic medicine research centers worldwide.
Introduction
Genomic medicine deals with the application of the human genome research to the
medical practice. The genome is a complete set of DNA for a particular organism.
DNA-deoxyribonucleic acid-is made up of four chemicals called bases, abbreviated
as A, T, C, and G. The human genome has approximately 3 billion pairs of bases.
A Brief History
The United States Human
Genome Project formally began in 1990 under the coordination of the U.S.
Department of Energy (DoE) and the National
Institutes of Health (NIH). The major goals set were to identify all of the
approximately 30,000 genes in human DNA
and to determine the sequences of the 3 billion DNA base pairs that constitute
the human genome. The recent completion of the draft sequence has increased
interest in its application to the field of medicine. In 1999 the American
Society for Genomic Medicine was founded with the goal of promoting research in
genomic medicine and to facilitate public awareness of the benefits it may bring
to the humankind. The details of the working draft DNA sequence was published in
February 2001 by the Human Genome Project and Celera
Genomics, Inc. The first panoramic view of the human genetic landscape has
revealed a wealth of information presently under study.
Genomic Medical Physics
Medicine has now entered a new age whereby the patient's genome will be of
utmost importance for optimal health care, preventive, therapeutic, diagnostic,
and clinical, giving rise to Genomic Medicine. Many problems in Genomic Medicine
will be treated as subfield of physics,
biophysics,
chemical
physics, and other physics-related disciplines. A new field of physics is
emerging: Genomic Medical Physics.
Genomics and Pharmacogenomics
The successes of the Human Genome Project enable researchers to identify errors
in genes that cause or contribute to disease. All diseases have a genetic
component, whether inherited or resulting from the body's response to
environmental stresses such as viruses or toxins. A number of genes associated
with breast cancer, muscle disease, deafness, and blindness have been
identified. The explorations into the nature of human genome represent a major
challenge extending far into the twenty-first century. These explorations will
shed light on the role of faulty genes in disease causation. With this
knowledge, commercial efforts are shifting away from diagnostics and toward
developing a new generation of therapeutics based on genes. Drug designs—pharmacogenomics
are being revolutionized. Researchers are now creating new classes of medicines
based on information on gene sequence and protein structure function rather than
the traditional trial-and-error method. Drugs targeted to specific sites in the
body promise to have fewer side effects than many of today's medicines. Laser-guided
drug-delivery techniques have a high potential in targeting drugs to
specific sites in the body. One of the greatest impacts of research in Genomics
may prove to be an entirely new approach to biomedical
research. In the past, researchers studied one or a few genes at a time.
With whole-genome sequences they can approach problems systematically and on a
large scale. Presently, all the genes in a genome can be studied, as well as how
tens of thousands of genes and proteins work together via networks orchestrating
the physics of life.
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